EVALUATION OF 4 PREOPERATIVE LABORATORY MARKERS FOR IDENTIFICATION OF NUTRITIONAL ASPECTS IN THORACIC SURGERY COMPLICATIONS emmanuel.penag@incmnsz.mx

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EVALUATION OF 4 PREOPERATIVE LABORATORY MARKERS FOR IDENTIFICATION OF NUTRITIONAL ASPECTS IN THORACIC SURGERY COMPLICATIONS

4

 

 

 

 

Mexico

Oral or Poster

Surgeries for thoracic infections. have an intense inflammatory response that could negatively influence the postoperative outcomes. Obtain preoperative laboratory marker could help to identify patients at risk and improve the perioperative management.

retrospective analysis. 61 patients 24-hour preoperative laboratory evaluation was obtained in all the patients. We retrospectively calculated four indexes: Prognostic nutritional index, Neutrophile-to-lymphocyte ratio, Platelet-to-lymphocyte ratio, Platelet-to-neutrophile ratio.We performed a ROC curve,Youden’s index,Patients were divided in two groups, those with a high risk of poor postoperative outcomes and those with a low risk, based on the optimal cut-off value from each index. Chi-square and Fisher’s exact tests

The PNI, NLR and PNR had a great performance in the ROC curve analysis for the prediction of 30-day mortality and major complications (AUC 0.860 p=0.001, 0.870 p< 0.001, 0.846 p=0.001, while PLR had not (AUC 0.652 p=0.149). In the comparison by groups, the PNI < 28.35, NLR >7.81 and PNR < 37.21 were associated with greater 30-day postoperative mortality (p=0.002, OR 13.04, p< 0.001, OR 44, p< 0.001, OR 51.4 and major complications (p< 0.001, OR 8.75, p< 0.001, OR 8.8, p=0.003, OR 7.2. In the univariable analysis, only the PNI, NLR and PNR were statistically significant predictors of 30-day postoperative mortality,Chi-square and Fisher’s exact tests were performed to compare results between groups

The PNI, NLR and PNR are good predictors for 30-day postoperative mortality and major complications.the detection of patients at high risk for poor postoperative outcomes , improve the perioperative care for this population.