IMPACT OF BODY WEIGHT, FAT AND NUTRITION ONTO THE EPIDEMIOLOGY AND SURGICAL OUTCOME OF GASTRIC CANCER - REFLEXION OF MODERATELY AVAILABLE AND PARTIALLY INCONGRUENT LITERATURE DATA f.meyer@med.ovgu.de

PE082

IMPACT OF BODY WEIGHT, FAT AND NUTRITION ONTO THE EPIDEMIOLOGY AND SURGICAL OUTCOME OF GASTRIC CANCER - REFLEXION OF MODERATELY AVAILABLE AND PARTIALLY INCONGRUENT LITERATURE DATA

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Germany

Poster Exhibition only

Aim: To derive from the medical scientific literature and (preliminary) data, what impact the risk factor body weight associated with BMI and related aspects has for the treatment of gastric cancer.

Narrative review

Literature data indicates: - There are research groups, which do not associate an increased BMI with an increased perioperative risk, others consider a BMI > 30 kg/m2 as risk factor. - Another study stated that regarding the whole groups, there is no association of these factors in esophageal and gastric cancer - but there are subgroups with different proportions, e.g., cardia carcinoma. - As reason for potentially expanded tumor diseases in the group of overweight patients, increased portion of body fat, unhealthy nutrition (in particular, fat- and carbohydrate-enriched) as well as physical inactivity were described. - A further remarkable aspect is the visceral fat since in men, it is more meaningful than the body weight or BMI. - Other groups describe sarcopenia in overweight as risk factor. Own data seems to indicate that in preobesity (overweight), there is a higher risk for postoperative surgical complications, such as abdominal wound rupture or duodenal stump insufficiency - multivariable analysis revealed that BMI induced no impact onto morbidity and mortality; long-term outcome data seems to show that preobesity provides a better survival.

Combining the factors with an impact, body weight as well as the associated clinical manifestations of overweight or obesity are considered relevant influencing parameters, which - in part - are controversely discussed in the literature.