SURGICAL EFFICACY AND ASPECTS ADJUSTED TO RESECTION OF FIBROUS TUMOR OF THE PLEURA emmanuel.penag@incmnsz.mx

462-01

SURGICAL EFFICACY AND ASPECTS ADJUSTED TO RESECTION OF FIBROUS TUMOR OF THE PLEURA

6

 

 

 

 

Mexico

Oral or Poster

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm with variable anatomical location, unpredictable clinical behavior, and risk of recurrence or dissemination. Although most cases are localized and low-grade, some present aggressive or multifocal features, as in Doege–Potter syndrome. The use of nuclear STAT6 expression has improved diagnostic accuracy in differentiating SFT from other spindle cell tumors.

A clinical case series was conducted following CARE recommendations. Three male patients were included with a diagnosis of SFT in different thoracic locations: lingular pleura, left diaphragmatic pleura, and anterior mediastinum (as a recurrence of an IGF2-producing hepatic SFT). The surgical approach, intraoperative findings, histopathological studies, immunohistochemistry, and clinical course were documented in all cases, respecting ethical principles and obtaining verbal consent.

In case 1, video-assisted thoracoscopic resection of a low-grade pleural SFT was performed, with no complications or recurrence at six months. In case 2, a left thoracotomy was performed with resection of a high-grade infiltrating SFT (Ki-67 10%), with mild postoperative subcutaneous emphysema. The patient remains under multidisciplinary surveillance.

These cases demonstrate the clinical and anatomical variability of SFT, as well as the importance of an individualized surgical approach. Long-term follow-up is essential to detect recurrences and manage complications, given the unpredictable nature of these tumors