EFFICACY OF TRICLOSAN-COATED NON-ABSORBABLE SUTURES IN REDUCING SURGICAL SITE INFECTIONS: A RANDOMIZED CONTROLLED TRIAL somendrachauhan@hotmail.com

 

EFFICACY OF TRICLOSAN-COATED NON-ABSORBABLE SUTURES IN REDUCING SURGICAL SITE INFECTIONS: A RANDOMIZED CONTROLLED TRIAL

7

India

Oral only

Surgical site infections (SSIs) are a leading cause of postoperative morbidity and healthcare burden. Antimicrobial-coated sutures, such as triclosan-coated polydioxanone (PDS), have been proposed to reduce the risk of microbial colonization at wound sites. Objective: To evaluate the effectiveness of triclosan-coated non-absorbable PDS sutures in minimizing SSIs and enhancing postoperative outcomes in elective open abdominal surgeries.

In this double-blind randomized controlled trial, 72 patients undergoing elective open abdominal procedures were enrolled and randomly assigned to either the non-coated PDS group (Group A) or the triclosan-coated PDS group (Group B). Primary and secondary outcomes included SSI incidence (per CDC/Southampton criteria), wound healing, postoperative pain (VAS score), duration of hospitalization, complications, and patient satisfaction.

Group B demonstrated a significantly lower incidence of SSIs (16.7%) compared to Group A (40.0%; p = 0.02). Enhanced wound healing was observed in Group B (83.3% vs. 60.0%; p = 0.01), along with reduced pain scores on postoperative days 1, 3, and 7 (p < 0.05). The mean hospital stay was shorter in the triclosan group (6.97 vs. 9.75 days; p = 0.01), and patient satisfaction was higher.

Triclosan-coated PDS sutures significantly lower the risk of SSIs and contribute to improved recovery profiles. Their routine use in elective abdominal surgeries is recommended.