PAPILLARY CYSTITIS IN A CASE OF ADVANCED CERVICAL CANCER- A RARE DIAGNOSTIC CHALLENGE ntiamoaheffah@yahoo.com

PE062

PAPILLARY CYSTITIS IN A CASE OF ADVANCED CERVICAL CANCER- A RARE DIAGNOSTIC CHALLENGE

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Ghana

Oral or Poster

Papillary cystitis is a rare, benign, chronic inflammation of the bladder that can closely resemble urothelial bladder cancer both clinically and on imaging. We report a rare case of papillary cystitis in a patient with newly diagnosed cervical cancer

not applicable

Case report- A 52-year-old postmenopausal woman presented with severe dysuria, foul-smelling brownish vaginal discharge, and a sensation of incomplete bladder emptying. She had no history of hematuria or long-term catheter use. She had a firm suprapubic mass extending to the umbilicus. Abdominopelvic computed tomography scan revealed a large bladder wall mass narrowing the bladder lumen, bilateral hydronephroureters and extension of the mass toward the anterior uterus. Cystoscopy and examination under anesthesia showed a large papillary bladder mass involving the trigone, left lateral wall, and dome, along with an endophytic cervical lesion with pelvic sidewall involvement. The rectal examination was normal. Bladder biopsy showed a normal thickness urothelium with papillary projections, stromal edema, and infiltration by neutrophils and leukocytes, consistent with papillary cystitis. Cervical biopsy confirmed invasive squamous cell carcinoma

Although papillary cystitis may not be directly linked to cervical cancer, high-risk Human Papilloma Virus infection involving the urinary tract and direct irritation by the cervical cancer may play a role in its development. Histological confirmation of the benign bladder lesion was imperative especially in this case where the mass could have been considered as a primary malignancy or contiguous infiltration from the cervical cancer.