NON-INVASIVE PHYSICAL PLASMA APPLICATION AS AN ADJUVANT TREATMENT OF EPIFAST IN SUPERFICIAL AND DEEP SECOND-DEGREE BURNS pablomx1965@gmail.com

PW05-03

NON-INVASIVE PHYSICAL PLASMA APPLICATION AS AN ADJUVANT TREATMENT OF EPIFAST IN SUPERFICIAL AND DEEP SECOND-DEGREE BURNS

8

Mexico

Oral or Poster

The burn patient care in critical condition requires efficiency and innovation. The objective demonstrates that non-invasive physical plasma (NIPP) as adjuvant therapy to Epifast helps to improve the healing process in patients with second-degree burns.

For the generation of the NIPP in a reactor, helium was used as a working gas with a flow of 0.5 L/min. The patients were divided in a control group (Group 1: Scarectomy in the first 48 hour after burn and wound coverage with Epifast, evaluation of the wound after 5-6 days) and the experimental group that received the NIPP(Group 2 first application of NIPP and coverage the wound with Epifast, NIPP application every 24 hours and evaluation of the wound after 5-6 days).

Forty patients were included, 20 (Group 1), and 20 (Group 2). total body surface burn (TBSA) was 12.60%±8.2 for Group 1 and 12.55%±8.06 for Group 2. No adverse effects in any group. Stay hospital, analgesics and antibiotics were slightly less in the experimental group, although without significant statistical difference. Regarding the grafted patients, it was representative in favor of the experimental group since only two patients (10%) were grafted vs eight patients (40%) of the control group, with a relative risk (RR) of 0.25 and a 95% confidence interval (CI) ±0.06-1.0 (p=0.02).

The non-invasive physical plasma as adjuvant therapy of Epifast reduces the need for autografts in burn patients by 75%, with no incidence of adverse effects. Demonstrating its efficacy and safety in the treatment of superficial and deep second-degree burns.