PREVALENCE OF TRAUMA-INDUCED COAGULOPATHY DIAGNOSED USING THROMBOELASTOGRAPHY IN A REGIONAL HOSPITAL IN THE PHILIPPINES ralphtrinhermosisima@gmail.com

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PREVALENCE OF TRAUMA-INDUCED COAGULOPATHY DIAGNOSED USING THROMBOELASTOGRAPHY IN A REGIONAL HOSPITAL IN THE PHILIPPINES

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Philippines

Poster with Discussion

This study explores the prevalence of Trauma-Induced Coagulopathy (TIC) in Filipino patients admitted to a tertiary regional hospital. TIC is an abnormal coagulation process mainly attributed to severe traumatic injuries. The study used deranged parameters in thromboelastography (TEG) and prothrombin time with INR for conventional coagulation assay (CCA) to diagnose TIC.

From July 2023 to January 2024, sixty-six patients meeting trauma admission criteria had blood samples taken for TEG, CCA, arterial blood gas, and complete blood count simultaneously. TEG results were interpreted by an intensivist.

TIC was diagnosed in 45.45% of patients (30 individuals): 16.67% were diagnosed using only TEG, 22.72% using only CCA, and 6.06% using both. Mortality was highest when TIC was diagnosed using both assays (100%). When diagnosed using TEG and CCA separately, mortality was higher with TEG (45% vs 13%). Average lengths of stay were 14.6 days, 11 days, and less than 24 hours for those diagnosed with TIC using CCA, TEG, and both, respectively. Average initial blood transfusion requirements in the emergency department were 2 units each for patients with TIC diagnosed using CCA or TEG alone, and 5.5 units for patients diagnosed using both.

The prevalence of TIC is higher in this population than previously reported. Patients diagnosed with TIC had poorer outcomes, especially when diagnosed using both assays. TEG and CCA should be performed on severe trauma patients for guidance in resuscitation and prognostication.